Abstract: To study the matrix strength of the axial rotating heat pipe grinding wheel (HPGW) in the process of high efficiency profile grinding, and considering that HPGW has the characteristics of heat transfer enhancement, ANSYS workbench was used to perform finite element analysis on the HPGW under the thermo-mechanical coupling. At the rotating speed of 30 000 r/min, the maximum equivalent stress of HPGW is 26.481 MPa, and the maximum deformation is 0.014 8 mm, all of which meet the allowable requirements. The influence of rotating speed on maximum equivalent stress and deformation under the conditions of different grinding parameters, matrix materials and workpiece materials was discussed respectively. The results show that at the same feed rate and cutting depth, with the increase of the rotating speed, the maximum equivalent stress of HPGW decreases first and then increases, and the maximum deformation decreases continuously. HPGW with 2Cr13 as the matrix material adopts the creep feed deep grinding process to grind the titanium alloy, which can minimize the stress and deformation. The best parameters in this condition was rotating speed of n=10 000 r/min, workpiece speed of v_w=80 mm/min, and cutting depth of a_p=0.10 mm.